The effect of resistance training on blood pressure, apelin, ANP, PON1, adiponectin, H2O2, and ET-1 in hypertensive men

Background and aims: Primary hypertension, an unexplained increase in blood pressure (BP), accounts for 90% of the cases hypertension remains a critical public health challenge. This study aimed to investigate effects 12-week resistance training (RT) on some vasodilators vasoconstrictors hypertensive men. Methods: is semi-experimental study. A total 40 middle-aged men (45.3±3.2 years) with moderate (systolic BP [SBP] 140.5±0.3 diastolic [DBP] 90.7±0.0 mm Hg) were randomly divided into RT (n=20) non-exercise control groups. The dynamic program was performed at intensity 80% one repetition maximum 3 days per week (3 sets 8 repetitions/3 week). Blood samples taken from both groups baseline weeks 4, 8, 12. Results: SBP DBP decreased by -8.19±2.46 Hg (P=0.039) -1.19±0.02 (P=0.033) 12 group, respectively, compared group (SBP; 8.22±2.49, P=0.04; DBP; -1.19±0.03, P=0.032). Adiponectin, apelin, atrial natriuretic peptide (ANP), paraoxonase-1 (PON-1) serum levels increased (P=0.01) (P=0.01), while endothelin-1 (ET-1) H2 O2 comparison group. Conclusion: Overall, led ANP, PON-1, adiponectin. Increasing these markers reduces ET-1, thus decreasing